Differentiate between globular and fibrous proteins.
(i) Fibrous proteins: These proteins consist of linear thread like molecules which tend to lie side by side (parallel) to form fibres. The polypeptide chains in them are held together usually at many points by hydrogen bonds and some disulphide bonds. As a result,intermolecular forces of attraction are very’ strong and hence fibrous proteins are insoluble in water. Further, these proteins are stable to moderate changes in temperature and pH. Fibrous proteins serve as the chief structural material of animal tissues.For example, keratin in skin, hair, nails and wool, collagen in tendons, fibrosis in silk and myosin in muscles.
(ii) Globular proteins: The polypeptide chain in these proteins is folded around itself in such a way so as to give the entire protein molecule an almost spheroidal shape. The folding takes place in such a manner that hydrophobic (non-polar) parts are pushed inwards and hydrophilic (polar) parts are pushed outwards. As a result, water molecules interact strongly with the polar groups and hence globular protein are water soluble. As compared to fibrous proteins, these are very sensitive to small changes of temperature and pH. This class of proteins include all enzymes, many hormones such as insulin from pancreas, thyroglobulin from thyroid gland, etc.
The letters ' D ' or ' L' before the name of a stereoisomer of a compound indicate the correlation of configuration of that particular stereoisomer.
This refers to their relation with one of the isomers of glyceraldehydes. Predict whether the following compound has ‘D' or ‘L' configuration.
Which monosaccharide units are present in starch, cellulose and glycogen and which linkages link these units?
Which of the following terms are correct about enzyme?
(a) Proteins (b) Dinucleotides
(c) Nucleic acids (d) Biocatalysts
Assertion (A): Deoxyribose, C5H10O4 is not a carbohydrate.
Reason (R): Carbohydrates are hydrates of carbon so compounds which follow Cx(H2O)y formula are carbohydrates.
When RNA is hydrolysed, there is no relationship among the quantities of different bases obtained. What does this fact suggest about the structure of RNA?
Carbohydrates are classified on the basis of their behaviour on hydrolysis and also as reducing or non-reducing sugar. Sucrose is a .
(a) monosaccharide (b) disaccharide
(c) reducing sugar (d) non-reducing sugar
Aldopentoses named ribose and 2-deoxyribose are found in nucleic acids.
What is their relative configuration?
Assertion (A): Vitamin D can be stored in our body.
Reason (R): Vitamin D is fat soluble vitamin.
How do you explain the presence of all six carbon atoms in glucose in a straight chain?
Sucrose is dextrorotatory but the mixture obtained after hydrolysis is laevorotatory. Explain.
Which of the following carbohydrates are branched polymer of glucose?
(a) Amylose (b) Amylopectin (c) Cellulose (d) Glycogen
Match the vitamins given in Column I with the deficiency disease they cause given in Column II.
Assertion (A): All naturally occurring a-amino acids except glycine are optically active.
Reason (R): Most naturally occurring amino acids have L-configuration.
Three structures are given below in which two glucose units are linked. Which of these linkages between glucose units are between C1 and C4 and which linkages are between C1 and C6?
Which of the following monosaccharides are present as five membered cyclic structure (foranose structure)?
(a) Ribose (b) Glucose (c) Fructose (d) Galactose
Activation energy for the acid catalysed hydrolysis of sucrose is 6.22 kJ mol-1, while hydrolysis is catalysed by the enzyme sucrase. Explain.
Monosaccharides contain carbonyl group hence are classified, as aldose or ketose. The number of carbon atoms present in the monosaccharide molecule are also considered for classification. In which class of monosaccharide will you place fructose?
α-Helix is a secondary structure of proteins formed by twisting of polypeptide chain into right handed screw like structures. Which type of interactions are responsible for making the a-helix structure stable?
Assertion (A): Glycine must’be taken through diet.
Reason (R): It is an essential amino acid.
Some enzymes are named after the reaction, where they are used. What name is given to the class of enzymes which catalyse the oxidation of one substrate with simultaneous reduction of another substrate?
Structures of glycine and alanine are given below. Show the peptide linkage in glycylalanine.
Carbohydrates are essential for life in both plants and animals. Name the carbohydrates that are used as storage molecules in plants and animals, also name the carbohydrate which is present in wood or in the fibre of cotton cloth.
In fibrous proteins, polypeptide chains are held together by
(a) van der Waals forces (b) disulphide linkage
(c) electrostatic forces of attraction (d) hydrogen bonds
