What are enzyme inhibitors? Classify them on the basis of their mode of attachments on the active site of enzymes. With the help of diagrams explain how do inhibitors inhibit the enzymatic activity.
Ckemistnj in Evenjdai] Life 325
Enzyme inhibitors block the binding site of enzyme and prevent the binding of substrate and then inhibit the catalytic activity of enzyme. They act in two different ways.
(i) Drugs which compete with substrate for their attachment on the active sites of enzymes are called competitive inhibitor.
(ii) Some drugs bind to a different site of enzyme called allosteric site. It changes the shape of the active site and substrate cannot recognize it. Such enzymes are called non-competitive inhibitor the bond formed between enzyme and an inhibitor is strong covalent bond then enzyme is blocked permanently.
Assertion (A): Receptor proteins show selectivity for one chemical messenger over the other.
Reason (R): Chemical messenger binds to the receptor site and inhibits its natural function.
Between sodium hydrogen carbonate and magnesium hydroxide which is a better antacid and why?
While antacids and antiallergic drugs interfere with the function of histamines, why do these not interfere with the function of each other?
Assertion (A): Artificial sweeteners are added to the food to control the intake of calories.
Reason (R): Most of the artificial sweeteners are inert and do not metabolise in the body.
Aspirin is pain relieving antipyretic drug but can be used to prevent heart attack. Explain.
Which of the following are sulpha drugs?
(a) Sulphapyridine (b) Prontosil
(c) Salvarsan (d) Nardil
Which of the following are antidepressants?
(a) Iproniazid (b) Phenelzine (c) Equanil (d) Salvarsan
Assertion (A): Chemical messenger gives message to the cell without entering the cell.
Reason (R): Chemical messenger is received at the binding site of receptor proteins.
What is the advantage of using antihistamines over antacids in the treatment of acidity?
Sodium salts of some acids are Very useful as food preservatives. Suggest a few such acids.
What happens when the bond formed between an enzyme and an inhibitor is a strong covalent bond?
What are enzyme inhibitors? Classify them on the basis of their mode of attachments on the active site of enzymes. With the help of diagrams explain how do inhibitors inhibit the enzymatic activity.
Ckemistnj in Evenjdai] Life 325
With refrence to which classification has the statement "ranitidine is an antacid", been given?
Assertion (A): Competitive inhibitors compete with natural substrate for their attachment on the active sites of enzymes.
Reason (R): In competitive inhibition, inhibitor binds to the allosteric site of the enzyme.
Assertion (A): All chemicals added to food items are called food preservatives.
Reason (R): All these chemicals increase the nutritive value of the food.
Which of the following statements are incorrect about receptor proteins?
(a) Majority of receptor proteins are embedded in the cell membranes.
(b) The active site of receptor proteins opens on the inside region of the cell.
(c) Chemical messengers are received at the binding sites of receptor proteins.
(d) Shape of receptor does not change during attachment of messenger.
Which of the following statements are correct about barbiturates?
(a) Hypnotics or sleep producing agents.
(b) These are tranquilizers.
(c) Non-narcotic analgesics.
(d) Pain reducing without disturbing the nervous system.
Name two ct-amino acids which form a dipeptide which is 100 times more sweet than cane sugar?
Assertion (A): Sulpha drug contain sulphonamide group.
Reason (R): Salvarsan is a sulpha drug.
Assertion (A): Preservative are added to food items.
Reason (R): Preservatives inhibit the growth of microorganisms.
Synthetic detergents have advantage over usual soaps as far as cleansing power is concerned. But use of synthetic detergents over a long time creates environmental pollution. How can the pollution caused by synthetic detergents be minimized? Classify the detergents according to their chemical nature.
With refrence to which classification has the statement "ranitidine is an antacid", been given?
Compounds with antiseptic properties are
(a) CHCl, (b) CHI3
(c) Boric acid (d) 0.3 ppm aqueous solution of Cl2