Match the class of compounds given in Column I with their functions given in Column II.
(i -> b), (ii —> d), (iii —> a), (iv —> e), (v —> c)
(i) Antagonist drugs are used when blocking of message is required. For example, dopamine antagonist is a drug which blocks the dopamine receptors by receptor antagonism.
(ii) Agonist drugs are useful when there is lack of chemical messenger, e.g., heroin.
(iii) These chemical messengers are received at the binding sites of receptor. These communicate message between two neurons and that between neurons to muscles.
(iv) Inhibitors block the binding site of the enzyme and prevent the binding of the substrate, or inhibit the catalytic activity of the enzyme.
(v) Receptors are proteins that are crucial to body's communication. They are embedded in the cell membrane in such a way that their small part possessing active site projects out of the surface of the membrane and opens on the outside region of the cell membrane.
Which of the following are anionic detergents?
(a) Sodium salts of sulphonated long chain alcohol.
(b) Ester of stearic acid and polyethylene glycol.
(c) Quaternary ammonium salt of amine with acetate ion.
(d) Sodium salts of sulphonated long chain hydrocarbons.
Assertion (A): Transparent soaps are made by dissolving soaps in ethanol. Reason (R): Ethanol makes things invisible.
Why are cimetidine and ranitidine better antacids than sodium hydrogencarbonate or magnesium or aluminium hydroxide?
Which of the following compounds are administered as ant-acids?
(a) Sodium carbonate (b)Sodium Hydrogen carbonate
(c)Aluminium carbonate (d)Magnism Hydroxide
In the following questions, a statement of Assertion (A) followed by a statement of Reason (R) is given. Choose the correct answer out of the following choices:
(a) Assertion and reason both are correct statements but reason does not explain assertion.
(b) Assertion and reason-both are correct statements and reason explains the assertion.
(c) Both assertion and reason are wrong statement.
(d) Assertion is correct statement and reason is wrong statements.
(e) Assertion is wrong statements and reason is correct statement.
Assertion (A): Penicillin (G) is an antihistamine.
Reason (R): Penicillin (G) is effective against gram positive as well as gram negative bacteria. .
While antacids and antiallergic drugs interfere with the function of histamines, why do these not interfere with the function of each other?
Which of the following statements are correct about barbiturates?
(a) Hypnotics or sleep producing agents.
(b) These are tranquilizers.
(c) Non-narcotic analgesics.
(d) Pain reducing without disturbing the nervous system.
Assertion (A): Preservative are added to food items.
Reason (R): Preservatives inhibit the growth of microorganisms.
Synthetic detergents have advantage over usual soaps as far as cleansing power is concerned. But use of synthetic detergents over a long time creates environmental pollution. How can the pollution caused by synthetic detergents be minimized? Classify the detergents according to their chemical nature.
Which of the following are not used as food preservatives?
(a) Table salt (b) Sodium hydrogen carbonate
(c) Cane sugar (d) Benzoic acid
Name two ct-amino acids which form a dipeptide which is 100 times more sweet than cane sugar?
Assertion (A): Receptors are crucial to body's communication process. Reason (R): Receptors are proteins.
Assertion (A): Chemical messengers are chemicals that enable communi ¬cation of message between two neutrons or between neurons and muscles. Reason (R): Chemicals enter the cell through receptor.
Assertion (A): Non-competitive inhibitor inhibits the catalytic activity of enzyme by binding with its active site.
Reason (R): Non-competitive inhibitors changes the shape of the active site in such a way that substrate cannot recognize it.
Assertion (A): Receptor proteins show selectivity for one chemical messenger over the other.
Reason (R): Chemical messenger binds to the receptor site and inhibits its natural function.
How do enzymes catalyse a chemical reaction in the living system? Explain drug target interaction taking the example of enzyme as target.
Sleeping pills are recommended by doctors to the patients suffering from sleeplessness but it is not advisable to take its doses without consultation with the doctor. Why?
Compounds with antiseptic properties are
(a) CHCl, (b) CHI3
(c) Boric acid (d) 0.3 ppm aqueous solution of Cl2
Which of the following are antidepressants?
(a) Iproniazid (b) Phenelzine (c) Equanil (d) Salvarsan
