Chemistry

Biomolecules

Question:

Protein found in a biological system with a unique three dimensional structure and biological activity is called a native protein. When a protein in its native form, is subjected to a physical change like change in temperature or a chemical change like, change in pH, denaturation of protein takes place. Explain the cause.

Answer:

Due to physical or chemical change, hydrogen bonding and various other attractive forces are disturbed, globules unfold and helix gets uncoiled to form a thread like molecule. Therefore, secondary and tertiary structure of protein loses all or part of their biological activity. This is called denaturation of proteins.

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Biomolecules

Q 1.

The letters ' D ' or ' L' before the name of a stereoisomer of a compound indicate the correlation of configuration of that particular stereoisomer.
ncert-exemplar-problems-class-12-chemistry-biomolecules-21
This refers to their relation with one of the isomers of glyceraldehydes. Predict whether the following compound has ‘D' or ‘L' configuration.

Q 2.

During curdling of milk, what happens to sugar present in it?

Q 3.

What are essential and non-essential amino acids? Give two examples of each type.

Q 4.

Which monosaccharide units are present in starch, cellulose and glycogen and which linkages link these units?

Q 5.

Which of the following terms are correct about enzyme?
(a) Proteins (b) Dinucleotides
(c) Nucleic acids (d) Biocatalysts

Q 6.

Describe the term D- and L-configuration used for amino acids with examples.

Q 7.

Where does the water present in the egg go after boiling the egg?

Q 8.

When RNA is hydrolysed, there is no relationship among the quantities of different bases obtained. What does this fact suggest about the structure of RNA?

Q 9.

Assertion (A): Vitamin D can be stored in our body.
Reason (R): Vitamin D is fat soluble vitamin.

Q 10.

Assertion (A): Deoxyribose, C5H10O4 is not a carbohydrate.
Reason (R): Carbohydrates are hydrates of carbon so compounds which follow Cx(H2O)y formula are carbohydrates.

Q 11.

Name the linkage connecting monosaccharide units in polysaccharides.

Q 12.

What are the common types of secondary structure of proteins?

Q 13.

Why does compound (A) given below not form an oxime?
ncert-exemplar-problems-class-12-chemistry-biomolecules-26

Q 14.

Sucrose is dextrorotatory but the mixture obtained after hydrolysis is laevorotatory. Explain.

Q 15.

Why are vitamin A and vitamin C essential to us? Give their important sources.

Q 16.

Why must vitamin C be supplied regularly in diet?

Q 17.

What is glycogen? How is it different from starch?

Q 18.

What is the difference between a nucleoside and a nucleotide?

Q 19.

Carbohydrates are classified on the basis of their behaviour on hydrolysis and also as reducing or non-reducing sugar. Sucrose is a .
(a) monosaccharide (b) disaccharide
(c) reducing sugar (d) non-reducing sugar

Q 20.

How do you explain the presence of all six carbon atoms in glucose in a straight chain?

Q 21.

ncert-exemplar-problems-class-12-chemistry-biomolecules-23

Q 22.

α-Helix is a secondary structure of proteins formed by twisting of polypeptide chain into right handed screw like structures. Which type of interactions are responsible for making the a-helix structure stable?

Q 23.

Match the vitamins given in Column I with the deficiency disease they cause given in Column II.
ncert-exemplar-problems-class-12-chemistry-biomolecules-37

Q 24.

What are enzymes?

Q 25.

Assertion (A): All naturally occurring a-amino acids except glycine are optically active.
Reason (R): Most naturally occurring amino acids have L-configuration.

Q 26.

ncert-exemplar-problems-class-12-chemistry-biomolecules-15

Q 27.

Aldopentoses named ribose and 2-deoxyribose are found in nucleic acids.
What is their relative configuration?

Q 28.

How do enzymes help a substrate to be attacked by the reagent effectively?

Q 29.

Differentiate between globular and fibrous proteins.

Q 30.

Three structures are given below in which two glucose units are linked. Which of these linkages between glucose units are between C1 and C4 and which linkages are between C1 and C6?
ncert-exemplar-problems-class-12-chemistry-biomolecules-12

Q 31.

Match the following enzyme given in Column I with the reactions they catalyse given in Column II.
ncert-exemplar-problems-class-12-chemistry-biomolecules-38

Q 32.

What are monosaccharides ?

Q 33.

What is the effect of denaturation on the structure of proteins?

Q 34.

What are nucleic acids ? Mention their two important functions.

Q 35.

How do you explain the presence of five -OH groups in glucose molecule?

Q 36.

Activation energy for the acid catalysed hydrolysis of sucrose is 6.22 kJ mol-1, while hydrolysis is catalysed by the enzyme sucrase. Explain.

Q 37.

Assertion (A): Glycine must’be taken through diet.
Reason (R): It is an essential amino acid.

Q 38.

Why cannot Vitamin C be stored in our body?

Q 39.

What type of bonding helps in stabilising the α-helix structure of proteins?

Q 40.

Which of the following monosaccharides are present as five membered cyclic structure (foranose structure)?
(a) Ribose (b) Glucose (c) Fructose (d) Galactose

Q 41.

Under what conditions glucose is converted to gluconic and saccharic acid?

Q 42.

Monosaccharides contain carbonyl group hence are classified, as aldose or ketose. The number of carbon atoms present in the monosaccharide molecule are also considered for classification. In which class of monosaccharide will you place fructose?  

Q 43.

Some enzymes are named after the reaction, where they are used. What name is given to the class of enzymes which catalyse the oxidation of one substrate with simultaneous reduction of another substrate?

Q 44.

Amino acids behave like salts rather than simple amines or carboxylic acids. Explain.

Q 45.

Structures of glycine and alanine are given below. Show the peptide linkage in glycylalanine.
ncert-exemplar-problems-class-12-chemistry-biomolecules-30

Q 46.

What are the expected products of hydrolysis of lactose?

Q 47.

What do you understand by the term glycosidic linkage?

Q 48.

In fibrous proteins, polypeptide chains are held together by
(a) van der Waals forces (b) disulphide linkage
(c) electrostatic forces of attraction (d) hydrogen bonds

Q 49.

In nucleoside a base is attached at 1′ position of sugar moiety. Nucleotide is formed by linking of phosphoric acid unit to the sugar unit of nucleoside. At which position of sugar unit is the phosphoric acid linked in a nucleoside to give a nucleotide?

Q 50.

Assertion (A): β-glycosidic linkage is present in maltose.
ncert-exemplar-problems-class-12-chemistry-biomolecules-39
Reason (R): Maltose is composed of two glucose units in which C-l of one glucose unit is linked to C-4 of another glucose unit.