Chemistry

Biomolecules

Question:

Protein found in a biological system with a unique three dimensional structure and biological activity is called a native protein. When a protein in its native form, is subjected to a physical change like change in temperature or a chemical change like, change in pH, denaturation of protein takes place. Explain the cause.

Answer:

Due to physical or chemical change, hydrogen bonding and various other attractive forces are disturbed, globules unfold and helix gets uncoiled to form a thread like molecule. Therefore, secondary and tertiary structure of protein loses all or part of their biological activity. This is called denaturation of proteins.

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Biomolecules

Q 1.

The letters ' D ' or ' L' before the name of a stereoisomer of a compound indicate the correlation of configuration of that particular stereoisomer.
ncert-exemplar-problems-class-12-chemistry-biomolecules-21
This refers to their relation with one of the isomers of glyceraldehydes. Predict whether the following compound has ‘D' or ‘L' configuration.

Q 2.

How do enzymes help a substrate to be attacked by the reagent effectively?

Q 3.

During curdling of milk, what happens to sugar present in it?

Q 4.

What are the common types of secondary structure of proteins?

Q 5.

What are essential and non-essential amino acids? Give two examples of each type.

Q 6.

Which sugar in called invert sugar? Why is it called so?

Q 7.

Which monosaccharide units are present in starch, cellulose and glycogen and which linkages link these units?

Q 8.

Assertion (A): Vitamin D can be stored in our body.
Reason (R): Vitamin D is fat soluble vitamin.

Q 9.

What is glycogen? How is it different from starch?

Q 10.

What are enzymes?

Q 11.

Name the linkage connecting monosaccharide units in polysaccharides.

Q 12.

ncert-exemplar-problems-class-12-chemistry-biomolecules-23

Q 13.

Where does the water present in the egg go after boiling the egg?

Q 14.

Differentiate between globular and fibrous proteins.

Q 15.

Why are vitamin A and vitamin C essential to us? Give their important sources.

Q 16.

Why must vitamin C be supplied regularly in diet?

Q 17.

Which of the following terms are correct about enzyme?
(a) Proteins (b) Dinucleotides
(c) Nucleic acids (d) Biocatalysts

Q 18.

Why does compound (A) given below not form an oxime?
ncert-exemplar-problems-class-12-chemistry-biomolecules-26

Q 19.

Assertion (A): Glycine must’be taken through diet.
Reason (R): It is an essential amino acid.

Q 20.

Why cannot Vitamin C be stored in our body?

Q 21.

When RNA is hydrolysed, there is no relationship among the quantities of different bases obtained. What does this fact suggest about the structure of RNA?

Q 22.

Describe the term D- and L-configuration used for amino acids with examples.

Q 23.

What type of bonding helps in stabilising the α-helix structure of proteins?

Q 24.

What is the difference between a nucleoside and a nucleotide?

Q 25.

The two strands in DNA are not identical but are complementary. Explain.

Q 26.

Three structures are given below in which two glucose units are linked. Which of these linkages between glucose units are between C1 and C4 and which linkages are between C1 and C6?
ncert-exemplar-problems-class-12-chemistry-biomolecules-12

Q 27.

What is the effect of denaturation on the structure of proteins?

Q 28.

Carbohydrates are classified on the basis of their behaviour on hydrolysis and also as reducing or non-reducing sugar. Sucrose is a .
(a) monosaccharide (b) disaccharide
(c) reducing sugar (d) non-reducing sugar

Q 29.

What products would be formed when a nucleotide from DNA containing thymine is hydrolysed?

Q 30.

What do you understand by the term glycosidic linkage?

Q 31.

What is the basic structural difference between starch and cellulose?

Q 32.

Write the important structural and functional differences between DNA and RNA.

Q 33.

Which of the following carbohydrates are branched polymer of glucose?
(a) Amylose (b) Amylopectin (c) Cellulose (d) Glycogen

Q 34.

In fibrous proteins, polypeptide chains are held together by
(a) van der Waals forces (b) disulphide linkage
(c) electrostatic forces of attraction (d) hydrogen bonds

Q 35.

How do you explain the presence of all six carbon atoms in glucose in a straight chain?

Q 36.

Monosaccharides contain carbonyl group hence are classified, as aldose or ketose. The number of carbon atoms present in the monosaccharide molecule are also considered for classification. In which class of monosaccharide will you place fructose?  

Q 37.

Aldopentoses named ribose and 2-deoxyribose are found in nucleic acids.
What is their relative configuration?

Q 38.

Some enzymes are named after the reaction, where they are used. What name is given to the class of enzymes which catalyse the oxidation of one substrate with simultaneous reduction of another substrate?

Q 39.

Structures of glycine and alanine are given below. Show the peptide linkage in glycylalanine.
ncert-exemplar-problems-class-12-chemistry-biomolecules-30

Q 40.

Assertion (A): β-glycosidic linkage is present in maltose.
ncert-exemplar-problems-class-12-chemistry-biomolecules-39
Reason (R): Maltose is composed of two glucose units in which C-l of one glucose unit is linked to C-4 of another glucose unit.

Q 41.

Assertion (A): All naturally occurring a-amino acids except glycine are optically active.
Reason (R): Most naturally occurring amino acids have L-configuration.

Q 42.

What are the expected products of hydrolysis of lactose?

Q 43.

Classify the following into monosaccharides and disaccharides. Ribose, 2-deoxyribose, maltose, galactose, fructose and lactose.

Q 44.

Which of the following pairs represents anomers?
ncert-exemplar-problems-class-12-chemistry-biomolecules-3
ncert-exemplar-problems-class-12-chemistry-biomolecules-4

Q 45.

Which of the following monosaccharides are present as five membered cyclic structure (foranose structure)?
(a) Ribose (b) Glucose (c) Fructose (d) Galactose

Q 46.

Under what conditions glucose is converted to gluconic and saccharic acid?

Q 47.

α-Helix is a secondary structure of proteins formed by twisting of polypeptide chain into right handed screw like structures. Which type of interactions are responsible for making the a-helix structure stable?

Q 48.

Protein found in a biological system with a unique three dimensional structure and biological activity is called a native protein. When a protein in its native form, is subjected to a physical change like change in temperature or a chemical change like, change in pH, denaturation of protein takes place. Explain the cause.

Q 49.

Assertion (A): Deoxyribose, C5H10O4 is not a carbohydrate.
Reason (R): Carbohydrates are hydrates of carbon so compounds which follow Cx(H2O)y formula are carbohydrates.

Q 50.

Glucose or sucrose are soluble in water but cyclohexane and benzene (simple six membred ring compounds) are insoluble in water Explain.