Differentiate between globular and fibrous proteins.
(i) Fibrous proteins: These proteins consist of linear thread like molecules which tend to lie side by side (parallel) to form fibres. The polypeptide chains in them are held together usually at many points by hydrogen bonds and some disulphide bonds. As a result,intermolecular forces of attraction are very’ strong and hence fibrous proteins are insoluble in water. Further, these proteins are stable to moderate changes in temperature and pH. Fibrous proteins serve as the chief structural material of animal tissues.For example, keratin in skin, hair, nails and wool, collagen in tendons, fibrosis in silk and myosin in muscles.
(ii) Globular proteins: The polypeptide chain in these proteins is folded around itself in such a way so as to give the entire protein molecule an almost spheroidal shape. The folding takes place in such a manner that hydrophobic (non-polar) parts are pushed inwards and hydrophilic (polar) parts are pushed outwards. As a result, water molecules interact strongly with the polar groups and hence globular protein are water soluble. As compared to fibrous proteins, these are very sensitive to small changes of temperature and pH. This class of proteins include all enzymes, many hormones such as insulin from pancreas, thyroglobulin from thyroid gland, etc.
Assertion (A): Deoxyribose, C5H10O4 is not a carbohydrate.
Reason (R): Carbohydrates are hydrates of carbon so compounds which follow Cx(H2O)y formula are carbohydrates.
Aldopentoses named ribose and 2-deoxyribose are found in nucleic acids.
What is their relative configuration?
Three structures are given below in which two glucose units are linked. Which of these linkages between glucose units are between C1 and C4 and which linkages are between C1 and C6?
Assertion (A): Vitamin D can be stored in our body.
Reason (R): Vitamin D is fat soluble vitamin.
Which monosaccharide units are present in starch, cellulose and glycogen and which linkages link these units?
Assertion (A): In presence of enzyme, substrate molecule can be attacked by the reagent effectively.
Reason (R): Active sites of enzymes hold the substrate molecule in a suitable position.
Name the sugar present in milk. How many monosaccharide units are present in it? What are such oligosaccharides called?
Assertion (A): Glycine must’be taken through diet.
Reason (R): It is an essential amino acid.
The letters ' D ' or ' L' before the name of a stereoisomer of a compound indicate the correlation of configuration of that particular stereoisomer.
This refers to their relation with one of the isomers of glyceraldehydes. Predict whether the following compound has ‘D' or ‘L' configuration.
Structure of a disaccharide formed by glucose and fructose is given below. Identify anomeric carbon atoms in monosaccharide units.
Which of the following carbohydrates are branched polymer of glucose?
(a) Amylose (b) Amylopectin (c) Cellulose (d) Glycogen
Structures of glycine and alanine are given below. Show the peptide linkage in glycylalanine.
In disaccharides, if the reducing groups of monosaccharides, i.e., aldehydic or ketonic groups are bonded, these are non-reducing sugars. Which of the following disaccharide is a non-reducing sugar?
Carbohydrates are classified on the basis of their behaviour on hydrolysis and also as reducing or non-reducing sugar. Sucrose is a .
(a) monosaccharide (b) disaccharide
(c) reducing sugar (d) non-reducing sugar
Which of the following monosaccharides are present as five membered cyclic structure (foranose structure)?
(a) Ribose (b) Glucose (c) Fructose (d) Galactose
Match the vitamins given in Column I with the deficiency disease they cause given in Column II.
Assertion (A): All naturally occurring a-amino acids except glycine are optically active.
Reason (R): Most naturally occurring amino acids have L-configuration.
Coagulation of egg white on boiling is an example of denaturation of protein. Explain it in terms of structural changes.
Assertion (A): β-glycosidic linkage is present in maltose.
Reason (R): Maltose is composed of two glucose units in which C-l of one glucose unit is linked to C-4 of another glucose unit.
Carbohydrates are essential for life in both plants and animals. Name the carbohydrates that are used as storage molecules in plants and animals, also name the carbohydrate which is present in wood or in the fibre of cotton cloth.
When RNA is hydrolysed, there is no relationship among the quantities of different bases obtained. What does this fact suggest about the structure of RNA?
How are vitamins classified? Name the vitamin responsible for the coagulation of blood.
How will you distinguish 1 ° and 2 ° hydroxyl groups present in glucose? Explain with reactions.
What products would be formed when a nucleotide from DNA containing thymine is hydrolysed?
What happens when D-glucose is treated with . the following reagents.
(i)HI (ii) Bromine water (iii) HNO3
Enumerate the reactions of D-glucose which cannot be explained by its open chain structure.
Optical rotations of some compounds along with their structures are given below which of them have D configuration.
Amino acids are classified as acidic, basis or neutral depending upon the relative number of amino and carboxyl groups in their molecule. Which of the following are acidic?
How do you explain the presence of all six carbon atoms in glucose in a straight chain?
