Chemistry

Biomolecules

Question:

The two strands in DNA are not identical but are complementary. Explain.

Answer:

he two strands in DNA molecule are held together by hydrogen bonds between purine base of one strand and pyrimidine base of the other and vice versa. Because of different sizes and geometries of the bases, the only possible pairing in DNA are G (guanine) and C (cytosine) through three H-bonds, (i.e.,C = G) and between A (adenine) and T (thiamine) through two H-bonds (i.e., A = T). Due to this base -pairing principle, the sequence of bases in one strand automatically fixes the sequence of bases in the other strand. Thus, the two strands are complimentary and not identical.

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Biomolecules

Q 1.

The letters ' D ' or ' L' before the name of a stereoisomer of a compound indicate the correlation of configuration of that particular stereoisomer.
ncert-exemplar-problems-class-12-chemistry-biomolecules-21
This refers to their relation with one of the isomers of glyceraldehydes. Predict whether the following compound has ‘D' or ‘L' configuration.

Q 2.

How do enzymes help a substrate to be attacked by the reagent effectively?

Q 3.

Which of the following pairs represents anomers?
ncert-exemplar-problems-class-12-chemistry-biomolecules-3
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Q 4.

During curdling of milk, what happens to sugar present in it?

Q 5.

Name the linkage connecting monosaccharide units in polysaccharides.

Q 6.

What are the common types of secondary structure of proteins?

Q 7.

Which monosaccharide units are present in starch, cellulose and glycogen and which linkages link these units?

Q 9.

Assertion (A): Vitamin D can be stored in our body.
Reason (R): Vitamin D is fat soluble vitamin.

Q 10.

Which sugar in called invert sugar? Why is it called so?

Q 11.

What is glycogen? How is it different from starch?

Q 12.

Why does compound (A) given below not form an oxime?
ncert-exemplar-problems-class-12-chemistry-biomolecules-26

Q 13.

What are essential and non-essential amino acids? Give two examples of each type.

Q 14.

Differentiate between globular and fibrous proteins.

Q 15.

Describe the term D- and L-configuration used for amino acids with examples.

Q 16.

Classify the following into monosaccharides and disaccharides. Ribose, 2-deoxyribose, maltose, galactose, fructose and lactose.

Q 17.

What are the hydrolysis products of (i) sucrose, and (ii) lactose?

Q 18.

What are enzymes?

Q 19.

How do you explain the presence of all six carbon atoms in glucose in a straight chain?

Q 20.

α-Helix is a secondary structure of proteins formed by twisting of polypeptide chain into right handed screw like structures. Which type of interactions are responsible for making the a-helix structure stable?

Q 21.

Some enzymes are named after the reaction, where they are used. What name is given to the class of enzymes which catalyse the oxidation of one substrate with simultaneous reduction of another substrate?

Q 22.

Why must vitamin C be supplied regularly in diet?

Q 23.

Protein found in a biological system with a unique three dimensional structure and biological activity is called a native protein. When a protein in its native form, is subjected to a physical change like change in temperature or a chemical change like, change in pH, denaturation of protein takes place. Explain the cause.

Q 24.

Assertion (A): β-glycosidic linkage is present in maltose.
ncert-exemplar-problems-class-12-chemistry-biomolecules-39
Reason (R): Maltose is composed of two glucose units in which C-l of one glucose unit is linked to C-4 of another glucose unit.

Q 25.

Assertion (A): Glycine must’be taken through diet.
Reason (R): It is an essential amino acid.

Q 26.

What are the different types of RNA found in the cell?

Q 27.

In fibrous proteins, polypeptide chains are held together by
(a) van der Waals forces (b) disulphide linkage
(c) electrostatic forces of attraction (d) hydrogen bonds

Q 28.

Which of the following terms are correct about enzyme?
(a) Proteins (b) Dinucleotides
(c) Nucleic acids (d) Biocatalysts

Q 29.

Match the following enzyme given in Column I with the reactions they catalyse given in Column II.
ncert-exemplar-problems-class-12-chemistry-biomolecules-38

Q 30.

What are the expected products of hydrolysis of lactose?

Q 31.

Where does the water present in the egg go after boiling the egg?

Q 32.

What products would be formed when a nucleotide from DNA containing thymine is hydrolysed?

Q 33.

When RNA is hydrolysed, there is no relationship among the quantities of different bases obtained. What does this fact suggest about the structure of RNA?

Q 34.

What are reducing sugars?

Q 35.

What is the basic structural difference between starch and cellulose?

Q 36.

What type of bonding helps in stabilising the α-helix structure of proteins?

Q 37.

Why are vitamin A and vitamin C essential to us? Give their important sources.

Q 38.

Optical rotations of some compounds along with their structures are given below which of them have D configuration.
ncert-exemplar-problems-class-12-chemistry-biomolecules-10

Q 39.

Carbohydrates are classified on the basis of their behaviour on hydrolysis and also as reducing or non-reducing sugar. Sucrose is a .
(a) monosaccharide (b) disaccharide
(c) reducing sugar (d) non-reducing sugar

Q 40.

Proteins can be classified into two types on the basis of their molecular shape, i.e., fibrous proteins and globular proteins. Examples of globular proteins are
(a) insulin (b) keratin (c) albumin (d) myosin

Q 41.

Which of the following carbohydrates are branched polymer of glucose?
(a) Amylose (b) Amylopectin (c) Cellulose (d) Glycogen

Q 42.

Assertion (A): All naturally occurring a-amino acids except glycine are optically active.
Reason (R): Most naturally occurring amino acids have L-configuration.

Q 43.

Assertion (A): In presence of enzyme, substrate molecule can be attacked by the reagent effectively.
Reason (R): Active sites of enzymes hold the substrate molecule in a suitable position.

Q 44.

Why cannot Vitamin C be stored in our body?

Q 45.

How do you explain the amphoteric behaviour of amino acids?

Q 46.

What is the effect of denaturation on the structure of proteins?

Q 47.

Amino acids are classified as acidic, basis or neutral depending upon the relative number of amino and carboxyl groups in their molecule. Which of the following are acidic?
ncert-exemplar-problems-class-12-chemistry-biomolecules-13

Q 48.

ncert-exemplar-problems-class-12-chemistry-biomolecules-15

Q 49.

Which of the following monosaccharides are present as five membered cyclic structure (foranose structure)?
(a) Ribose (b) Glucose (c) Fructose (d) Galactose

Q 50.

In nucleoside a base is attached at 1′ position of sugar moiety. Nucleotide is formed by linking of phosphoric acid unit to the sugar unit of nucleoside. At which position of sugar unit is the phosphoric acid linked in a nucleoside to give a nucleotide?