Chemistry

Biomolecules

Question:

What is the difference between a nucleoside and a nucleotide?

Answer:

A nucleoside contains only two basic components of nucleic acids i.e., a pentose sugar and a nitrogenous base. It is formed when 1- position of pyrimidine (cytosine, thiamine or uracil) or 9-position of purine (guanine or adenine) base is attached to C -1 of sugar (ribose or deoxyribose) by a β-linkage. Nucleic acids are also called polynucleotides since the repeating structural unit of nucleic acids is a nucleotide.
A nucleotide contains all the three basic . components of nucleic acids, i.e., a phosphoric acid group, a pentose sugar and a nitrogenous base. These are obtained by esterification of C5, – OH group of the pentose sugar by phosphoric acid.
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Biomolecules

Q 1.

What are essential and non-essential amino acids? Give two examples of each type.

Q 2.

Aldopentoses named ribose and 2-deoxyribose are found in nucleic acids.
What is their relative configuration?

Q 3.

During curdling of milk, what happens to sugar present in it?

Q 4.

Assertion (A): Deoxyribose, C5H10O4 is not a carbohydrate.
Reason (R): Carbohydrates are hydrates of carbon so compounds which follow Cx(H2O)y formula are carbohydrates.

Q 5.

Three structures are given below in which two glucose units are linked. Which of these linkages between glucose units are between C1 and C4 and which linkages are between C1 and C6?
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Q 6.

Describe the term D- and L-configuration used for amino acids with examples.

Q 7.

When RNA is hydrolysed, there is no relationship among the quantities of different bases obtained. What does this fact suggest about the structure of RNA?

Q 8.

What is glycogen? How is it different from starch?

Q 9.

How do you explain the presence of all six carbon atoms in glucose in a straight chain?

Q 10.

Which monosaccharide units are present in starch, cellulose and glycogen and which linkages link these units?

Q 11.

Why are vitamin A and vitamin C essential to us? Give their important sources.

Q 12.

The letters ' D ' or ' L' before the name of a stereoisomer of a compound indicate the correlation of configuration of that particular stereoisomer.
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This refers to their relation with one of the isomers of glyceraldehydes. Predict whether the following compound has ‘D' or ‘L' configuration.

Q 13.

Assertion (A): Vitamin D can be stored in our body.
Reason (R): Vitamin D is fat soluble vitamin.

Q 14.

Which of the following terms are correct about enzyme?
(a) Proteins (b) Dinucleotides
(c) Nucleic acids (d) Biocatalysts

Q 15.

Why does compound (A) given below not form an oxime?
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Q 16.

Where does the water present in the egg go after boiling the egg?

Q 17.

What is the difference between a nucleoside and a nucleotide?

Q 18.

Assertion (A): β-glycosidic linkage is present in maltose.
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Reason (R): Maltose is composed of two glucose units in which C-l of one glucose unit is linked to C-4 of another glucose unit.

Q 19.

What type of bonding helps in stabilising the α-helix structure of proteins?

Q 20.

What is the effect of denaturation on the structure of proteins?

Q 21.

Under what conditions glucose is converted to gluconic and saccharic acid?

Q 22.

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Q 23.

How are vitamins classified? Name the vitamin responsible for the coagulation of blood.

Q 24.

Carbohydrates are classified on the basis of their behaviour on hydrolysis and also as reducing or non-reducing sugar. Sucrose is a .
(a) monosaccharide (b) disaccharide
(c) reducing sugar (d) non-reducing sugar

Q 25.

How do enzymes help a substrate to be attacked by the reagent effectively?

Q 26.

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Q 27.

Which of the following are purine bases?
(a) Guanine (b) Adenine (c) Thymine (d) Uracil

Q 28.

Name the linkage connecting monosaccharide units in polysaccharides.

Q 29.

Sucrose is dextrorotatory but the mixture obtained after hydrolysis is laevorotatory. Explain.

Q 30.

Carbohydrates are essential for life in both plants and animals. Name the carbohydrates that are used as storage molecules in plants and animals, also name the carbohydrate which is present in wood or in the fibre of cotton cloth.

Q 31.

Write two main functions of carbohydrates in plants.

Q 32.

What are the common types of secondary structure of proteins?

Q 33.

Which of the following carbohydrates are branched polymer of glucose?
(a) Amylose (b) Amylopectin (c) Cellulose (d) Glycogen

Q 34.

What are the expected products of hydrolysis of lactose?

Q 35.

What do you understand by the term glycosidic linkage?

Q 36.

Write the important structural and functional differences between DNA and RNA.

Q 37.

In disaccharides, if the reducing groups of monosaccharides, i.e., aldehydic or ketonic groups are bonded, these are non-reducing sugars. Which of the following disaccharide is a non-reducing sugar?
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Q 38.

In fibrous proteins, polypeptide chains are held together by
(a) van der Waals forces (b) disulphide linkage
(c) electrostatic forces of attraction (d) hydrogen bonds

Q 39.

Name the sugar present in milk. How many monosaccharide units are present in it? What are such oligosaccharides called?

Q 40.

Some enzymes are named after the reaction, where they are used. What name is given to the class of enzymes which catalyse the oxidation of one substrate with simultaneous reduction of another substrate?

Q 41.

Structures of glycine and alanine are given below. Show the peptide linkage in glycylalanine.
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Q 42.

Assertion (A): All naturally occurring a-amino acids except glycine are optically active.
Reason (R): Most naturally occurring amino acids have L-configuration.

Q 43.

Assertion (A): In presence of enzyme, substrate molecule can be attacked by the reagent effectively.
Reason (R): Active sites of enzymes hold the substrate molecule in a suitable position.

Q 44.

What happens when D-glucose is treated with . the following reagents.
(i)HI (ii) Bromine water (iii) HNO3

Q 45.

How do you explain the amphoteric behaviour of amino acids?

Q 46.

What are enzymes?

Q 47.

In nucleoside a base is attached at 1′ position of sugar moiety. Nucleotide is formed by linking of phosphoric acid unit to the sugar unit of nucleoside. At which position of sugar unit is the phosphoric acid linked in a nucleoside to give a nucleotide?

Q 48.

Amino acids behave like salts rather than simple amines or carboxylic acids. Explain.

Q 49.

How do you explain the presence of an aldehydic group in a glucose molecule?

Q 50.

What are monosaccharides ?